Pka value of sildenafil citrate

Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.

Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.

*****Other uses Âb

Use Sildenafil even if you don’t have medical help or access to medical o chances are you’ve taken an PDE5 inhibitor before. This is usually due to an interaction, but it’s rare, and you’ll start using Sildenafil on its own or with an adder-mover (such as in ED treatment)

The recommended starting dose is 50mg, taken 1-3 hours before sexual activity, but can be increased to 100mg or decreased to 25mg if needed.

How to take Sildenafil:

Use the dosing cup to measure your dose. This is called a dosing stick. begin by taking Sildenafil to be sure the medication is working, then use that stick for consistency. Do not exceed the recommended dose.

If your stick doesn’t give you the dosing you’ve been seeking, you can either:

  • Discontinue use and consult a doctor if symptoms persist or if you’ve had side effects from Sildenafil
  • Or,
  • Take your next dose at your normal time. Do not take a double dose to make up for a forgotten dose.

While you’re on Sildenafil, you should not take more than one dose a day.

Cautions and side effects:

  • Potential side effects of Sildenafil are not well understood, but are feel free to discuss them with your doctor.
  • If you have any health concerns, mention them to your doctor. They’ll be able toi check how you’relused Sildenafil and what’s most likely your health concerns with your doctor.
  • Remember, Sildenafil dosing is an oral liquid and so the pharmacist will likely start you on a lower dose andppy before you visit your doctor.
  • Sudden decrease or stopping of blood pressure or heart rate with combination medications is possible, but consult your doctor if these possibilities are severe.

Possible side effects:

Note: If you get side effects that get into your regular use stick (such as dizziness, feeling tired, experiencing high blood pressure, experiencing chest pain, nausea, or fainting), avoid using Sildenafil with themi.

  • Using Sildenafil with nitrates can cause a dangerous drop in blood pressure.
  • Avoid using Sildenafil with nitrates used for treating chest pain.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

Take Control of Your Sex Life

Don’t let ED affect your confidence or relationships. Buy Sildenafil tablets online today and experience more satisfying erections — securely, discreetly, and from our trusted UK-regulated pharmacy.

✅ Free online consultation✅ Fast UK delivery✅ Discreet packaging✅ GPhC-regulated

now and get back to enjoying intimacy with confidence.

Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.

References: ( amber light)

... read: 1-3/4-5 hours, can be more than 3-5/6-8/7-9/10/10/10/15/20/30/40/50/60/70/90/110/ 150mg, 50mg, and 100mg.

Read more

read: 1/2-3/4-5/6/7/8/9/10/15/20/30/40/50/60/70/90/100mg

Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Viagra use include:

  • Headache
  • Heartburn
  • Congestion
  • Nasal bleeding (bloody nose)
  • Nausea
  • Diarrhea
  • Muscle aches or pains
  • Flushing
  • Facial pain or tenderness
  • Vision changes
  • Light sensitivity

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Show More Degenerationriale Symptomatie Viagra Viagra

Potent erectile dysfunction medication like Viagra can help men overcome erectile dysfunction by increasing blood flow to the penis, causing an erection. This can help them achieve and maintain a firm erection.

However, Viagra offers a risk-benefit balance. Men who use Viagra less often report a lower likelihood of achieving and maintaining an erection when exposed to erectile dysfunction medications. Viagra can also exacerbate underlying health conditions such as heart disease or high blood pressure.

Viagra Side Effects

The most common side effects of Viagra are lightheaded, fainting, headache, flushing, and indigestion. These side effects typically subside within 24 hours of starting treatment, but they are generally mild to moderate in severity. However, sexual dysfunction can remain hidden from health care providers for several days after beginning treatment.

If you experience lightheadedness, fainting, headache, flushing, or a rapid heartbeat, contact your doctor immediately. If these side effects persist, initiate your treatment with your next available dose of Viagra. As with all prescription medications, inform your doctor of all your medical conditions.

If you experience changes in your heart rate or heartbeat, contact your health care provider immediately.

In contrast, Viagra offers a sedative effect. Men who take Viagra more than twice a day report a feeling of drowsiness and a slow heartbeat that can last for several hours. As a result, they are more likely to use Viagra when exposed to erectile dysfunction medications, leading to potentially serious adverse effects.

If you experience dizziness, lightheadedness, fainting, headache, flushing, dizziness, or a rush of dizziness or headache, contact your health care provider immediately. As with any prescription drug, inform your health care provider of all your medical conditions.

In addition, let your doctor know if you are pregnant or plan to become pregnant. Viagra can affect the developing penis if taken during pregnancy, so men who are pregnant or planning to become pregnant must use Viagra as directed. If you become pregnant, contact your health care provider immediately.

Viagra 50mg Side Effects

Potent erectile dysfunction medication like Viagra can help men who experience erectile dysfunction by increasing blood flow to the penis, causing an erection.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

Take Control of Your Sex Life

Don’t let ED affect your confidence or relationships. Buy Sildenafil tablets online today and experience more satisfying erections — securely, discreetly, and from our trusted UK-regulated pharmacy.

✅ Free online consultation✅ Fast UK delivery✅ Discreet packaging✅ GPhC-regulated

now and get back to enjoying intimacy with confidence.

Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.

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More information about Sildenafil

Cold Sore

Sildenafil is a medication that belongs to the class of PDE5 inhibitors, which work by relaxing the blood vessels in the penis, allowing for increased blood flow and the ability to achieve and maintain an erection.

Cold Sore is a prescription-only medicine used to treat erectile dysfunction in men. It works by enhancing the action of phosphodiesterase type 5 (PDE5) responsible for breaking down cyclic guanosine monophosphate (cGMP).

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Sildenafil. Side effects can include:

  • Headache
  • Back pain
  • Muscle pain
  • Flushing
  • Headache/Flush
  • Upset stomach
  • Upset stomach with light-headedness or nausea
  • Vomiting
  • Stuffy nose

Some of the most popular side effects of Sildenafil are:

  • Sudden loss of vision
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful or difficult breathing
  • Chest pain that doesn't go away
  • Rash, hives, or open chest
  • Difficulty in breathing
  • Fainting
  • Swelling

If you experience any of these side effects or have them listed as "Yes", "No", or "Moderate" in the patient information leaflet, patients should contact their doctor or pharmacist.

After taking Sildenafil, patients can have their vision tested by a doctor or pharmacist. If the results of their vision tests aren't positive, they should proceed to the emergency room or seek immediate medical attention.